Is sh-Polypeptide-121 fungal acne safe?

No, sh-Polypeptide-121 is considered a trigger for fungal acne (Malassezia) as it typically contains lipids or esters that feed the yeast.

Is sh-Polypeptide-121 safe for pregnancy?

Yes, sh-Polypeptide-121 is generally considered safe for use during pregnancy.

Is sh-Polypeptide-121 vegan?

No, sh-Polypeptide-121 is typically derived from animal sources.

Is sh-Polypeptide-121 comedogenic?

No, sh-Polypeptide-121 has a low comedogenic rating of 0/5 and is unlikely to clog pores.

sh-Polypeptide-121

HumaColl21

Good

Safe

Pores

0/5

Irritancy

0/5

FA Safe

❌ No

Pregnancy

✅ Safe

Vegan

❌ No

Science & Benefits

A first-of-its-kind bio-designed human collagen fragment produced via fermentation. It is 100% vegan and identical to a portion of human Collagen Type 21. It is zero-comedogenic. Its logic in an acne database is its ability to boost skin elasticity and facilitate faster tissue remodeling, which is vital for preventing atrophic (pitted) scarring after a severe inflammatory breakout.

Safety Alerts

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Fungal Acne: This ingredient is a lipid/ester that can feed Malassezia yeast. Avoid if you have active FA bumps.

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Non-Vegan: This ingredient is typically derived from animal sources (e.g. beeswax, lanolin, carmine).