Is Dipalmitoyl Hydroxyproline fungal acne safe?

No, Dipalmitoyl Hydroxyproline is considered a trigger for fungal acne (Malassezia) as it typically contains lipids or esters that feed the yeast.

Is Dipalmitoyl Hydroxyproline safe for pregnancy?

Yes, Dipalmitoyl Hydroxyproline is generally considered safe for use during pregnancy.

Is Dipalmitoyl Hydroxyproline vegan?

No, Dipalmitoyl Hydroxyproline is typically derived from animal sources.

Is Dipalmitoyl Hydroxyproline comedogenic?

No, Dipalmitoyl Hydroxyproline has a low comedogenic rating of 0/5 and is unlikely to clog pores.

Dipalmitoyl Hydroxyproline

Sepilift DPHP

Good

Safe

Pores

0/5

Irritancy

0/5

FA Safe

❌ No

Pregnancy

✅ Safe

Vegan

❌ No

Science & Benefits

Dipalmitoyl Hydroxyproline is a lipo-amino acid that combines hydroxyproline with palmitic acid to ensure deep penetration into the dermal layers. It is clinically recognized for its 'lifting' effect by protecting elastin fibers from enzymatic degradation and boosting collagen synthesis. Despite the palmitic acid component, its unique structure ensures it is non-comedogenic and zero-irritant. It provides intensive, long-lasting hydration and is an 'intellectual' choice for addressing both acne-prone skin and the loss of firmness (inflamm-aging), offering structural support without the need for heavy, pore-clogging creams.

Safety Alerts

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Fungal Acne: This ingredient is a lipid/ester that can feed Malassezia yeast. Avoid if you have active FA bumps.

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Non-Vegan: This ingredient is typically derived from animal sources (e.g. beeswax, lanolin, carmine).